Bright Futures: Cancer Research Great Opportunity

Aug. 6, 2013 - by Carol Best

REU Experience Solidifies Grad's Future Plans

July 11, 2013
20131105 THageman

Tyler Hageman (’13) loves the problem-solving aspect of chemistry. In fact he’s decided to be a research chemist instead of his original career plan of becoming a pharmacist. Getting to do original research at MNU with his professor, Dr. Faith Jacobsen, played big a part in that decision. Even more integral was Tyler’s summer 2012 experience as one of ten undergraduates chosen for the Research Experience for Undergraduates (REU) program at Miami University, Oxford, Ohio.

Recognizing Tyler’s passion for chemistry research, Jacobsen recommended him for the prestigious program where a colleague is doing research similar to her own.

“These REU positions are highly competitive and typically 150-200 students from around the country compete for only 10 spots, so we were of course thrilled that Tyler was selected,” Jacobsen said.

Tyler was chosen to work with Dr. David  Tierney, associate professor of chemistry and biochemistry, based on academic accomplishments, faculty recommendations and a letter of application. The REU summer program is funded by the National Science Foundation and allows students the opportunity to work with faculty mentors, perform research, hear from well-known scientists and even present at a scientific symposium.

“My academics, work experience and interest to explore chemistry research are three factors that led to being chosen for this,” Tyler says. “I did a semester of research at MNU with Dr. Jacobsen prior to the REU. I am studying matrix metalloproteinase (MMP). MMPs are enzymes in the human body that regulate processes such as tissue restructuring, wound healing and angiogenesis (the development of new blood vessels).”

Tyler’s particular area of research dealt with zinc’s influence on MMPs.

tylerHageman-10Tyler Hageman preparing/mixing a complex (mimic of the enzyme being studied) with an inhibitor.

“The reason why this regulation of this specific enzyme is of interest to scientists is people diagnosed with cancer have more MMP activity in the body than normal,” Tyler says. “MMPs assist in tumor development. The idea is to find a way to inhibit these enzymes for people diagnosed with cancer in order to slow or limit their activity which might hopefully limit tumor growth.”

It’s not as if Tyler took a bottle off the shelf and started researching though.

“I basically started from scratch and made a compound that has been known to be a good inhibitor,” He says. “It took me much of the semester to perfect making this compound. Once I made the compound I mailed it to Dr. Tierney in Ohio to use in his lab.”

While at Miami University Tyler focused on the characteristics of the models they would use in research.

“Again I had to design a way to make a unique model from scratch,” he said. “This took me the whole summer to perfect. Dr. Tierney did further studies with the model I made and is publishing a paper about it soon.”

Back at MNU last year Tyler researched the actual inhibition of these models and hopes his research will someday contribute to effective treatment for cancer. No matter what, he says his MNU education prepared him for the REU.

“I am exploring what inhibitors there are in this area of research and how effectively they inhibit models of the MMP enzyme,” he says. “MNU definitely prepared me for the research experience. As a junior in college I was presented with a real world problem in active research and was expected to contribute to that area of research.” 

Tyler says the all these experiences have helped him solidify his future plans.

“I have also learned a lot about graduate school and the process to obtain a PhD in chemistry as well as a lot about the scientific community,” he says. “Another great experience was to get in front of real people and present my research numerous times. It is a great feeling to throw everything I worked so hard on out on the table and try to wow them with the accomplishments I have made in that area of research.”

“I plan to attend the University of Kansas graduate school for the PhD program in chemistry and have already accepted my offer to attend there in the fall (2013).”

In addition to hours spent in the lab and in coursework, Tyler Hageman was a defender for the Pioneers men’s soccer team.

 

MNU News

Monday, December 5
Recent News
List
Grid
Archives
Straley-5
Alum Mixes Faith and Forensic Science

Alum Mixes Faith and Forensic Science

When forensic science comes to mind, scenes from CSI and NCIS may flash before your eyes. What you might not think about is one’s faith. But 2015 alum Hannah Straley has figured out how to balance…

Read More
GivingTuesday IG-firstphoto
Today is MNU Giving Tuesday

Today is MNU Giving Tuesday

Today is Giving Tuesday, the global day of giving fueled by social media and the collective support of millions. MNU’s goal is to reach 500 donations today and here’s how you can participate. All…

Read More
Spittal Official Headshot 2012 small edited
Spittal Elected to Second Five-Year Term at MNU

Spittal Elected to Second Five-Year Term at MNU

MidAmerica Nazarene University’s Board of Trustees unanimously passed a renewal vote for a five-year term of its fifth president, Dr. David J.…

Read More
Cunninghams 2014 Cathedral Builders Award
Student Center To Be Named After Cunninghams

Student Center To Be Named After Cunninghams

When MNU’s Bright Futures: the campaign for MNU was announced last month, many were delighted to hear that the new Student Center would be named…

Read More
IMG 0115
Scholarship Challenge Set for Jan. 27-28, 2017

Scholarship Challenge Set for Jan. 27-28, 2017

MNU’s second annual Scholarship Challenge is set for Jan. 27-28, 2017. The best and brightest high school seniors can compete at this year’s…

Read More
GivingTuesday IG-firstphoto-v2
Giving Tuesday is Nov. 29 at MNU

Giving Tuesday is Nov. 29 at MNU

Giving Tuesday, the global day of giving fueled by social media and the collective support of millions, is Nov. 29. This year MNU will participate in the philanthropic movement now in its fifth year.…

Read More
Emily Phillips 1
Senior’s Compassion Grows Through Internships

Senior’s Compassion Grows Through Internships

When student Emily Phillips went to Greece to intern with Nazarene Compassionate Ministries in the Syrian refugee camps, she wasn’t expecting her…

Read More
Students Walking
MNU Receives $300K from Sunderland Foundation for New Student Center

MNU Receives $300K from Sunderland Foundation for New Student Center

The proposed Cunningham Student Center is part of the new Bright Futures: the campaign for MNU, a three-priority, multi-year campaign for $61…

Read More
Nursing Sim I
Collaboration with Olathe Fire Department Makes Realistic Simulation for Students

Collaboration with Olathe Fire Department Makes Realistic Simulation for Students

Yesterday the Olathe Fire Department participated in a collaborative simulation with pre licensure nursing students at MNU. For students it started…

Read More
Sports
Pioneers Hit 8 National Qualifying Marks in Opener

Pioneers Hit 8 National Qualifying Marks in Opener

Track and Field season is officially underway. The Pioneer men and women showed out in their first meet at KU this weekend...(click title for more)

 
Pioneers Drop Tight Road Contest

Pioneers Drop Tight Road Contest

#8 MBB at Missouri Valley | L 76-80

 
Huge 4th Quarter Keys Road Win

Huge 4th Quarter Keys Road Win

MNU trailed by 9 points late in the third quarter, but a 21-3 run put the Pioneers in control in a 78-72 victory at Missouri Valley on Saturday...(click title for more)

 
Latest Photos
Olathe Mayor's Christmas Tree Lighting
Ice Skating
Ice Skating
Ice Skating
Thrid Half
Thrid Half