Bright Futures: Cancer Research Great Opportunity

Aug. 6, 2013 - by Carol Best

REU Experience Solidifies Grad's Future Plans

July 11, 2013
20131105 THageman

Tyler Hageman (’13) loves the problem-solving aspect of chemistry. In fact he’s decided to be a research chemist instead of his original career plan of becoming a pharmacist. Getting to do original research at MNU with his professor, Dr. Faith Jacobsen, played big a part in that decision. Even more integral was Tyler’s summer 2012 experience as one of ten undergraduates chosen for the Research Experience for Undergraduates (REU) program at Miami University, Oxford, Ohio.

Recognizing Tyler’s passion for chemistry research, Jacobsen recommended him for the prestigious program where a colleague is doing research similar to her own.

“These REU positions are highly competitive and typically 150-200 students from around the country compete for only 10 spots, so we were of course thrilled that Tyler was selected,” Jacobsen said.

Tyler was chosen to work with Dr. David  Tierney, associate professor of chemistry and biochemistry, based on academic accomplishments, faculty recommendations and a letter of application. The REU summer program is funded by the National Science Foundation and allows students the opportunity to work with faculty mentors, perform research, hear from well-known scientists and even present at a scientific symposium.

“My academics, work experience and interest to explore chemistry research are three factors that led to being chosen for this,” Tyler says. “I did a semester of research at MNU with Dr. Jacobsen prior to the REU. I am studying matrix metalloproteinase (MMP). MMPs are enzymes in the human body that regulate processes such as tissue restructuring, wound healing and angiogenesis (the development of new blood vessels).”

Tyler’s particular area of research dealt with zinc’s influence on MMPs.

tylerHageman-10Tyler Hageman preparing/mixing a complex (mimic of the enzyme being studied) with an inhibitor.

“The reason why this regulation of this specific enzyme is of interest to scientists is people diagnosed with cancer have more MMP activity in the body than normal,” Tyler says. “MMPs assist in tumor development. The idea is to find a way to inhibit these enzymes for people diagnosed with cancer in order to slow or limit their activity which might hopefully limit tumor growth.”

It’s not as if Tyler took a bottle off the shelf and started researching though.

“I basically started from scratch and made a compound that has been known to be a good inhibitor,” He says. “It took me much of the semester to perfect making this compound. Once I made the compound I mailed it to Dr. Tierney in Ohio to use in his lab.”

While at Miami University Tyler focused on the characteristics of the models they would use in research.

“Again I had to design a way to make a unique model from scratch,” he said. “This took me the whole summer to perfect. Dr. Tierney did further studies with the model I made and is publishing a paper about it soon.”

Back at MNU last year Tyler researched the actual inhibition of these models and hopes his research will someday contribute to effective treatment for cancer. No matter what, he says his MNU education prepared him for the REU.

“I am exploring what inhibitors there are in this area of research and how effectively they inhibit models of the MMP enzyme,” he says. “MNU definitely prepared me for the research experience. As a junior in college I was presented with a real world problem in active research and was expected to contribute to that area of research.” 

Tyler says the all these experiences have helped him solidify his future plans.

“I have also learned a lot about graduate school and the process to obtain a PhD in chemistry as well as a lot about the scientific community,” he says. “Another great experience was to get in front of real people and present my research numerous times. It is a great feeling to throw everything I worked so hard on out on the table and try to wow them with the accomplishments I have made in that area of research.”

“I plan to attend the University of Kansas graduate school for the PhD program in chemistry and have already accepted my offer to attend there in the fall (2013).”

In addition to hours spent in the lab and in coursework, Tyler Hageman was a defender for the Pioneers men’s soccer team.

 

MNU News

Saturday, March 28
Recent News
List
Grid
Archives
WoSBanner
Week of Scholarship April 7-10

Week of Scholarship April 7-10

MNU’s second annual Week of Scholarship is April 7 through 10, 2015, and highlights student and faculty achievement at MNU. The public is encouraged to attend and most events are free of…

Read More
7x7logo 1
7X7 Challenge Returns On April 7

7X7 Challenge Returns On April 7

MNU’s exciting 7X7 Challenge is back April 7, at 7:07 p.m. in Bell Cultural Events Center. Watch then vote for your favorite presenter when 7 MNU professors each give 7-minute presentations. Enjoy…

Read More
Andrew Ballew
Alum Says Community Makes the Difference

Alum Says Community Makes the Difference

Andrew Ballew, Psychology ’06, describes his job as continually changing and unpredictable from day to day, “one day I could be ducking under the thrown toys of a 6 year old in the morning and in…

Read More
Marge Smith, MNU Founding First Lady
Remembering A Modern Day Pioneer: Marge Smith

Remembering A Modern Day Pioneer: Marge Smith

Margaret “Marge” Emma Camfield Smith, age 96, of Olathe, Kansas, beloved founding first lady of MidAmerica Nazarene University, went to be with…

Read More
From Left to Right: Mayor Copeland, Mrs. Marge Smith, and Drs. Paul and Connie Cunningham
MNU Mourns Passing of Founding First Lady

MNU Mourns Passing of Founding First Lady

Marge Smith, wife of founding president, Dr. R. Curtis Smith, passed away quietly on Sunday, March 15, 2015 at the age of 96.  Surrounded by her…

Read More
PhilipWhite WhistleStop
Author and Alum Phillip White at MNU March 26

Author and Alum Phillip White at MNU March 26

Phillip White, celebrated author of his new book, Whistle Stop: How 31,000 Miles of Train Travel, 352 Speeches, and a Little Midwest Gumption Saved…

Read More
Game Pieces Icon
Grant to Fund Resource on Games and Learning

Grant to Fund Resource on Games and Learning

MNU is the recipient of a $5,000 Carnegie-Whitney Grant from the American Library Association to develop an annotated bibliography on analog games…

Read More
AurelienNorest2
Norest Most Decorated Soccer Player

Norest Most Decorated Soccer Player

Aurelien "Frenchy" Norest is the most decorated individual player in the 13-year history of MNU Men's Soccer. In his four years at MNU, the defenseman helped lead the program to four straight…

Read More
NAIA-Basketball-D1-Womens-2015 SGK
Women's Basketball Tourney in Independence

Women's Basketball Tourney in Independence

Women's basketball (26-5) plays in the NAIA DI National Tournament which begins Wednesday, March 18 at the Independence Events Center  in…

Read More
Sports
Gameday Central

Gameday Central

BB at Peru State | Peru, NE | 1:00/3:30Game 1 Live Stats | Game 2 Live StatsGame 1 Video | Game 2 VideoSB vs. CMU | Olathe, KS | 1:00/3:00Game 1 Live Stats | Game 2 Live StatsPSN Audio | HD Video (free preview)Twitter: @mnusports

 
Kevin Steele Named NAIA Under Armour AD of the Year

Kevin Steele Named NAIA Under Armour AD of the Year

MNU Director of Athletics, Kevin Steele, was named 2014-15 NAIA Under Armour AD of the Year...(click title for more)

 
Sprew, Balcom, Launius named All-America

Sprew, Balcom, Launius named All-America

Daria Sprew, Megan Balcom, and Nate Launius were named 2014-15 NAIA Division 1 All-America on Thursday...(click title for more)

 
Latest Photos
Midsummer Night's Dream 1770 Make up is applied for this stunning show back stage | Photo by Britney Lewis
Midsummer Night's Dream Make up is applied for this stunning show back stage | Photo by Britney Lewis
Midsummer Night's Dream 1778 Make up is applied for this stunning show back stage | Photo by Britney Lewis
Midsummer Night's Dream The blackbox transformed in this beautiful set. | Photo by Britney Lewis
Midsummer Night's Dream Make up is applied for this stunning show back stage | Photo by Britney Lewis
Midsummer Night's Dream Make up is applied for this stunning show back stage | Photo by Britney Lewis