Bright Futures: Cancer Research Great Opportunity

Aug. 6, 2013 - by Carol Best

REU Experience Solidifies Grad's Future Plans

July 11, 2013
20131105 THageman

Tyler Hageman (’13) loves the problem-solving aspect of chemistry. In fact he’s decided to be a research chemist instead of his original career plan of becoming a pharmacist. Getting to do original research at MNU with his professor, Dr. Faith Jacobsen, played big a part in that decision. Even more integral was Tyler’s summer 2012 experience as one of ten undergraduates chosen for the Research Experience for Undergraduates (REU) program at Miami University, Oxford, Ohio.

Recognizing Tyler’s passion for chemistry research, Jacobsen recommended him for the prestigious program where a colleague is doing research similar to her own.

“These REU positions are highly competitive and typically 150-200 students from around the country compete for only 10 spots, so we were of course thrilled that Tyler was selected,” Jacobsen said.

Tyler was chosen to work with Dr. David  Tierney, associate professor of chemistry and biochemistry, based on academic accomplishments, faculty recommendations and a letter of application. The REU summer program is funded by the National Science Foundation and allows students the opportunity to work with faculty mentors, perform research, hear from well-known scientists and even present at a scientific symposium.

“My academics, work experience and interest to explore chemistry research are three factors that led to being chosen for this,” Tyler says. “I did a semester of research at MNU with Dr. Jacobsen prior to the REU. I am studying matrix metalloproteinase (MMP). MMPs are enzymes in the human body that regulate processes such as tissue restructuring, wound healing and angiogenesis (the development of new blood vessels).”

Tyler’s particular area of research dealt with zinc’s influence on MMPs.

tylerHageman-10Tyler Hageman preparing/mixing a complex (mimic of the enzyme being studied) with an inhibitor.

“The reason why this regulation of this specific enzyme is of interest to scientists is people diagnosed with cancer have more MMP activity in the body than normal,” Tyler says. “MMPs assist in tumor development. The idea is to find a way to inhibit these enzymes for people diagnosed with cancer in order to slow or limit their activity which might hopefully limit tumor growth.”

It’s not as if Tyler took a bottle off the shelf and started researching though.

“I basically started from scratch and made a compound that has been known to be a good inhibitor,” He says. “It took me much of the semester to perfect making this compound. Once I made the compound I mailed it to Dr. Tierney in Ohio to use in his lab.”

While at Miami University Tyler focused on the characteristics of the models they would use in research.

“Again I had to design a way to make a unique model from scratch,” he said. “This took me the whole summer to perfect. Dr. Tierney did further studies with the model I made and is publishing a paper about it soon.”

Back at MNU last year Tyler researched the actual inhibition of these models and hopes his research will someday contribute to effective treatment for cancer. No matter what, he says his MNU education prepared him for the REU.

“I am exploring what inhibitors there are in this area of research and how effectively they inhibit models of the MMP enzyme,” he says. “MNU definitely prepared me for the research experience. As a junior in college I was presented with a real world problem in active research and was expected to contribute to that area of research.” 

Tyler says the all these experiences have helped him solidify his future plans.

“I have also learned a lot about graduate school and the process to obtain a PhD in chemistry as well as a lot about the scientific community,” he says. “Another great experience was to get in front of real people and present my research numerous times. It is a great feeling to throw everything I worked so hard on out on the table and try to wow them with the accomplishments I have made in that area of research.”

“I plan to attend the University of Kansas graduate school for the PhD program in chemistry and have already accepted my offer to attend there in the fall (2013).”

In addition to hours spent in the lab and in coursework, Tyler Hageman was a defender for the Pioneers men’s soccer team.

 

MNU News

Sunday, April 26
Recent News
List
Grid
Archives
TreePlanting4-21-2015-10 2
Tree Planting Honors Memory

Tree Planting Honors Memory

MNU honored the memory of three women from the School of Nursing with a tree planting at the close of Community Chapel April 21. Professor Delia Pittman, staff member Mrs. Janine McReynolds, and…

Read More
3D Car
MNU Awarded 3D Printers for Mabee Library

MNU Awarded 3D Printers for Mabee Library

MNU is the recent recipient of an in-kind grant of four 3D System “CUBE” printers, which will create a MakerSpace in Mabee Library. Pictured…

Read More
Pres Honors Stage
2015 President’s Honors Breaks Record

2015 President’s Honors Breaks Record

The fourth annual President’s Honors was a memorable night honoring individuals to whom the very existence of the university is owed. President David Spittal bestowed the Lifetime Achievement Award…

Read More
Blake Gold Brain
Blake Claims 7X7 Award

Blake Claims 7X7 Award

Tyler Blake, PhD, professor of English, and 1988 MNU grad, claimed the coveted Golden Brain Award at last week's 7X7 Challenge during MNU's second annual Week of Scholarship.  Blake's…

Read More
CD-Cover-Art
Choirs to Debut New CD at Concert

Choirs to Debut New CD at Concert

The Department of Fine and Performing Arts will debut their CD, On With the Show, at their annual pops concert Sunday, April 19 at 3:30 p.m. in Bell Cultural Events Center. The CD was recorded…

Read More
Presidents-1-2
Presidents On Campus for Gala

Presidents On Campus for Gala

On campus to attend President's Honors tonight are four of MNU's presidents. Enjoying the weather on the Campus Mall are current President David Spittal and past presidents Dr. Ed Robinson, Dr. Don…

Read More
Najarian from Outcomes Pub
MNU Alum Olathe Veterinarian Dr. Lisa Najarian

MNU Alum Olathe Veterinarian Dr. Lisa Najarian

It didn’t take holding down a lioness during surgery for Lisa Najarian, Biology Major ’07, to be affirmed in her calling. Usually it comes just…

Read More
Cunninghams LifetimeAchievementAward PH15
MNU Awards Lifetime Achievement to Drs. Paul G. and Connie R. Cunningham

MNU Awards Lifetime Achievement to Drs. Paul G. and Connie R. Cunningham

MNU will honor Drs. Paul G. and Connie R. Cunningham with the Lifetime Achievement Award at the 2015 President’s Honors April 10 in Cook Center at…

Read More
AcademicIcon
New Agreement Will Result in More Earned Degrees

New Agreement Will Result in More Earned Degrees

The Kansas Association of Community College Trustees (KACCT) and the Kansas Independent College Association (KICA), of which MNU is a member,…

Read More
Sports
Pioneers Take 3 of 4 at Benedictine

Pioneers Take 3 of 4 at Benedictine

The Pioneers went to Benedictine and swept a double header from the Ravens 7-4 and 6-3 on Friday, then split 2 games on Saturday...(click title for more)

 
Spring Game Slated for Saturday, April 25

Spring Game Slated for Saturday, April 25

Coach Brian Willmer and the 2014 HAAC Champs have announced the date for the Spring Game...(click title for more)

 
Pioneers Sweep on Senior Day

Pioneers Sweep on Senior Day

MNU trailed in both games, but came back in each to sweep Culver-Stockton on Senior Day...(click title for more)

 
Latest Photos
We :heart: MNUnursing As we celebrate National Nurse Appreciation Week, take a look at how nursing has changed at MNU over the years.
We :heart: MNUnursing As we celebrate National Nurse Appreciation Week, take a look at how nursing has changed at MNU over the years.
We :heart: MNUnursing As we celebrate National Nurse Appreciation Week, take a look at how nursing has changed at MNU over the years.
We :heart: MNUnursing As we celebrate National Nurse Appreciation Week, take a look at how nursing has changed at MNU over the years.
We :heart: MNUnursing As we celebrate National Nurse Appreciation Week, take a look at how nursing has changed at MNU over the years.
We :heart: MNUnursing As we celebrate National Nurse Appreciation Week, take a look at how nursing has changed at MNU over the years.