Bright Futures: Cancer Research Great Opportunity

Aug. 6, 2013 - by Carol Best

REU Experience Solidifies Grad's Future Plans

July 11, 2013
20131105 THageman

Tyler Hageman (’13) loves the problem-solving aspect of chemistry. In fact he’s decided to be a research chemist instead of his original career plan of becoming a pharmacist. Getting to do original research at MNU with his professor, Dr. Faith Jacobsen, played big a part in that decision. Even more integral was Tyler’s summer 2012 experience as one of ten undergraduates chosen for the Research Experience for Undergraduates (REU) program at Miami University, Oxford, Ohio.

Recognizing Tyler’s passion for chemistry research, Jacobsen recommended him for the prestigious program where a colleague is doing research similar to her own.

“These REU positions are highly competitive and typically 150-200 students from around the country compete for only 10 spots, so we were of course thrilled that Tyler was selected,” Jacobsen said.

Tyler was chosen to work with Dr. David  Tierney, associate professor of chemistry and biochemistry, based on academic accomplishments, faculty recommendations and a letter of application. The REU summer program is funded by the National Science Foundation and allows students the opportunity to work with faculty mentors, perform research, hear from well-known scientists and even present at a scientific symposium.

“My academics, work experience and interest to explore chemistry research are three factors that led to being chosen for this,” Tyler says. “I did a semester of research at MNU with Dr. Jacobsen prior to the REU. I am studying matrix metalloproteinase (MMP). MMPs are enzymes in the human body that regulate processes such as tissue restructuring, wound healing and angiogenesis (the development of new blood vessels).”

Tyler’s particular area of research dealt with zinc’s influence on MMPs.

tylerHageman-10Tyler Hageman preparing/mixing a complex (mimic of the enzyme being studied) with an inhibitor.

“The reason why this regulation of this specific enzyme is of interest to scientists is people diagnosed with cancer have more MMP activity in the body than normal,” Tyler says. “MMPs assist in tumor development. The idea is to find a way to inhibit these enzymes for people diagnosed with cancer in order to slow or limit their activity which might hopefully limit tumor growth.”

It’s not as if Tyler took a bottle off the shelf and started researching though.

“I basically started from scratch and made a compound that has been known to be a good inhibitor,” He says. “It took me much of the semester to perfect making this compound. Once I made the compound I mailed it to Dr. Tierney in Ohio to use in his lab.”

While at Miami University Tyler focused on the characteristics of the models they would use in research.

“Again I had to design a way to make a unique model from scratch,” he said. “This took me the whole summer to perfect. Dr. Tierney did further studies with the model I made and is publishing a paper about it soon.”

Back at MNU last year Tyler researched the actual inhibition of these models and hopes his research will someday contribute to effective treatment for cancer. No matter what, he says his MNU education prepared him for the REU.

“I am exploring what inhibitors there are in this area of research and how effectively they inhibit models of the MMP enzyme,” he says. “MNU definitely prepared me for the research experience. As a junior in college I was presented with a real world problem in active research and was expected to contribute to that area of research.” 

Tyler says the all these experiences have helped him solidify his future plans.

“I have also learned a lot about graduate school and the process to obtain a PhD in chemistry as well as a lot about the scientific community,” he says. “Another great experience was to get in front of real people and present my research numerous times. It is a great feeling to throw everything I worked so hard on out on the table and try to wow them with the accomplishments I have made in that area of research.”

“I plan to attend the University of Kansas graduate school for the PhD program in chemistry and have already accepted my offer to attend there in the fall (2013).”

In addition to hours spent in the lab and in coursework, Tyler Hageman was a defender for the Pioneers men’s soccer team.

 

MNU News

Friday, July 3
Recent News
List
Grid
Archives
Maker Faire 2015
Center for Games & Learning Wins Merit Award at KC Maker Faire

Center for Games & Learning Wins Merit Award at KC Maker Faire

The Center for Games & Learning booth won a Maker of Merit award at Maker Faire KC June 27 and 28 at Kansas City's Historic Union…

Read More
MNU-Fiber-Optics-Groundbreaking-062015
New Fiber Ring Installation Upgrades Campus

New Fiber Ring Installation Upgrades Campus

Installation is well underway for the new fiber optic network on the Olathe campus. Pictured below MNU President David Spittal and K&W…

Read More
UO8A0594 upcropped
Football Coach discovers joy of teaching

Football Coach discovers joy of teaching

  “Salt and light is all you can be at the end of the day,” said Ashford Collins (’12) as he sat in the same cafeteria where he used to share meals with his teammates. “When I came to…

Read More
Annie Kee
Alum Wins Stewardship Scholarship

Alum Wins Stewardship Scholarship

Andra Kee (‘13) is one of three winners of the Stewardship Sermon Scholarship awarded by Stewardship Ministries of the Church of the Nazarene. Funds for this scholarship are awarded annually to up…

Read More
outcomes-11
Compassion for Animals Leads to Career

Compassion for Animals Leads to Career

It didn’t take holding down a lioness during surgery for Lisa Najarian ('07), biology major, to be affirmed in her calling.  Usually it comes just seeing a four legged passenger with its head…

Read More
Facebook Infographic v3
MNU Announces Fully Online MBA

MNU Announces Fully Online MBA

New this fall at MNU is a fully online MBA program. The university has offered an MBA program for nearly 30 years, but until now all classes were held on site in Olathe or Liberty. Now students who…

Read More
Brandt Drafted
Brandt Drafted by Washington Nationals

Brandt Drafted by Washington Nationals

By Chad Jenkins, MNU SID Fans react on Storify hereMNU senior shortstop Clayton Brandt completed his incredible final season by getting selected in the 19th round by the Washington…

Read More
Jenkins Named HAAC SID of the Year

Jenkins Named HAAC SID of the Year

KANSAS CITY, Mo. - The Heart of America Athletic Conference has announced that Chad Jenkins, sports information director at MidAmerica Nazarene University, has been named the 2nd Annual Dave…

Read More
Hunting1sm
Success Means Doing One's Best

Success Means Doing One's Best

As a third grader, Stephen Hunting, considered a career as a lawyer.  But it took a year of seminary after graduating from MNU as a religion major, to realize law school was where God was…

Read More
Sports
Brittney Kellar Promoted to Assistant AD

Brittney Kellar Promoted to Assistant AD

Brittney Kellar has been promoted to Assistant Athletics Director for Business, Marketing and Event Management...(click title for more)

 
MNU Football Golf Tournament

MNU Football Golf Tournament

(click title for more)

 
MNU Women's Soccer Hires Bobby Reiss

MNU Women's Soccer Hires Bobby Reiss

MNU Women's soccer would like to say welcome to new assistant coach Bobby Reiss who will be taking over the assistant coaching duties...(click title for more)

 
Latest Photos
Sigma Theta Tau International (STTI) Chartering, 2014 MidAmerica Nazarene University’s School of Nursing and Health Science was recently approved to form a chapter of Sigma Theta Tau International (STTI), the honor society of nursing. Founded in 1922, STTI is recognized as the only international nursing honor society with approximately 500 chapters across the globe, only 5 of which are in Kansas. Photos by Daniel Hawkins and Justin Vargas
Sigma Theta Tau International (STTI) Chartering, 2014 MidAmerica Nazarene University’s School of Nursing and Health Science was recently approved to form a chapter of Sigma Theta Tau International (STTI), the honor society of nursing. Founded in 1922, STTI is recognized as the only international nursing honor society with approximately 500 chapters across the globe, only 5 of which are in Kansas. Photos by Daniel Hawkins and Justin Vargas
Sigma Theta Tau International (STTI) Chartering, 2014 MidAmerica Nazarene University’s School of Nursing and Health Science was recently approved to form a chapter of Sigma Theta Tau International (STTI), the honor society of nursing. Founded in 1922, STTI is recognized as the only international nursing honor society with approximately 500 chapters across the globe, only 5 of which are in Kansas. Photos by Daniel Hawkins and Justin Vargas
Sigma Theta Tau International (STTI) Chartering, 2014 MidAmerica Nazarene University’s School of Nursing and Health Science was recently approved to form a chapter of Sigma Theta Tau International (STTI), the honor society of nursing. Founded in 1922, STTI is recognized as the only international nursing honor society with approximately 500 chapters across the globe, only 5 of which are in Kansas. Photos by Daniel Hawkins and Justin Vargas
Sigma Theta Tau International (STTI) Chartering, 2014 MidAmerica Nazarene University’s School of Nursing and Health Science was recently approved to form a chapter of Sigma Theta Tau International (STTI), the honor society of nursing. Founded in 1922, STTI is recognized as the only international nursing honor society with approximately 500 chapters across the globe, only 5 of which are in Kansas. Photos by Daniel Hawkins and Justin Vargas
Sigma Theta Tau International (STTI) Chartering, 2014 MidAmerica Nazarene University’s School of Nursing and Health Science was recently approved to form a chapter of Sigma Theta Tau International (STTI), the honor society of nursing. Founded in 1922, STTI is recognized as the only international nursing honor society with approximately 500 chapters across the globe, only 5 of which are in Kansas. Photos by Daniel Hawkins and Justin Vargas